Oral Fluid Drug Testing Update: What DOT Safety-Sensitive Workers Need to Know

July 28, 2025

Ophthalmologist's Department

The Department of Transportation (DOT) has approved oral fluid (saliva) drug testing, but before it can officially be used in your required drug screening, a few key steps still need to be completed. Let’s break it down in plain language.

What’s Oral Fluid Testing?

It’s a drug test done with a mouth swab—no need to urinate in a cup. This method is more discreet, more accessible, and especially helpful for individuals with medical challenges that make urination difficult.

What’s Approved So Far?

DOT has already:

  1. Approved oral fluid testing as a valid method
  2. Selected and approved collection devices (the tools used to collect saliva)
  3. Created training requirements for collectors who will perform these tests

So yes, it’s on the way. But it’s not quite ready yet.

Why Isn’t It Available Yet?

DOT regulations require every drug test to have a split sample: one for the initial lab and one for backup testing in case of a dispute. That means two certified labs must be approved to process oral fluid samples. Currently, those final lab certifications are still pending. Until DOT officially greenlights two approved labs, oral fluid testing can’t be used for your drug screening.

When Will It Be Ready?

There’s no firm date yet. The rollout depends on lab certification, but updates are expected soon. Once approved, employers will likely begin offering oral testing options based on availability.

What This Means for You

For now:

  1. Continue completing urine-based drug tests as required
  2. If you have documented medical issues that affect your ability to provide a urine sample, let your SAP or MRO know

Oral testing will be a more convenient option, but only once DOT’s process is complete.

Final Thoughts

Yes, the wait can be frustrating but the system is designed to protect both employees and employers. Once oral fluid testing becomes official, it will provide a safer, more inclusive, and more accessible option for many safety-sensitive workers.

Karishma Sarfani

Karishma is a Qualified Substance Abuse Professional (SAP) with a background in mental health and substance abuse counseling, holding credentials as an MS, LCDC, ICADC, CADC II, CSAC, CASAC II, LPC, and EMDR-trained therapist. Inspired by personal experiences with addiction and mental health challenges in her community, she has dedicated her career to supporting individuals on their journey to recovery and success.